Optimized treatment program for unstable angina by integrative medicine based on partially observable Markov decision process / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
; (12): 878-882, 2013.
Article
en Zh
| WPRIM
| ID: wpr-359323
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To initially optimize comprehensive treatment program for treating and preventing unstable angina (UA) by integrative medicine (IM).</p><p><b>METHODS</b>Based on partially observable Markov decision process model (POMDP), we chose 3 syndrome elements, i.e., qi deficiency, blood stasis, and phlegm turbidity from UA inpatients. The efficacy of treating UA by IM was objectively assessed by in-depth data mining and analyses.</p><p><b>RESULTS</b>The treatment programs for UA patients of qi deficiency syndrome, blood stasis syndrome, and phlegm turbidity syndrome were recommended as follows: nitrates +statins +clopidogrel +angiotensin II receptor blockers +heparins +Astragalus membranaceus +Condonopsis + poria and large-head atractylodes rhizome (ADR = 0.85077869); nitrates + aspirin + clopidogrel + statins + heparins + Astragalus membranaceus + safflower + peach seed + red peony root (ADR = 0.70773000); nitrates + aspirin + statins + angiotensin-converting inhibitors + snakegourd fruit + onion bulb + ternate pinellia + tangerine peel (ADR = 0.72509600).</p><p><b>CONCLUSION</b>As a POMDP based optimized treatment programs for UA, it can be used as a reference for further standardization and formulation of UA program by integrative medicine.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Terapéutica
/
Cadenas de Markov
/
Sistemas de Apoyo a Decisiones Clínicas
/
Toma de Decisiones
/
Medicina Integrativa
/
Angina Inestable
Tipo de estudio:
Health_economic_evaluation
/
Prognostic_studies
Límite:
Humans
Idioma:
Zh
Revista:
Chinese Journal of Integrated Traditional and Western Medicine
Año:
2013
Tipo del documento:
Article