Updates in the research of relationship between MicroRNAs and hepatocellular carcinoma / 中华消化外科杂志

ABSTRACT

MicroRNAs are one kind of endogenous noncoding small-molecular RNAs,which play an important role in regulating gene expression,cell proliferation and differentiation and a series of life activity.Hepatocellular carcinoma is a common malignant and life-threatening tumor with a high incidence and low 5-year survival rate.In recent years,the results of researches show that microRNAs in hepatocellular carcinoma have the function of oncogenes or tumor suppressor genes as well as having a close relationship with the occurrence,progression,diagnosis,treatment and prognosis of hepatocellular carcinoma.