Advances in Study on Preventive Efficacy of Non-selective beta-Blockers in Patients with Esophageal Gastric Variceal Bleeding / 胃肠病学
Chinese Journal of Gastroenterology
; (12): 629-631, 2015.
Article
en Zh
| WPRIM
| ID: wpr-481060
Biblioteca responsable:
WPRO
ABSTRACT
Esophageal gastric variceal bleeding(EGVB)is a serious complication of cirrhotic portal hypertension with high mortality rate. Prevention of EGVB is an important mean to improve the survival of patients. Non-selective beta-blockers(NSBBs)is one of the first-line drugs for primary and secondary prevention of EGVB,however,only about 1 / 3 of cirrhotic patients respond to this treatment when evaluated by hepatic venous pressure gradient( HVPG). This may be related to the genetic polymorphisms of NSBBs’receptors and the metabolic enzymes. This article reviewed the progress in study on therapeutic efficacy of NSBBs and its influencing factors for preventing EGVB in cirrhotic patients.
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1
Base de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Gastroenterology
Año:
2015
Tipo del documento:
Article