Clinical efficacy and safety of doxazosin combined with desmopressin in treatment of nocturia in patients with benign prostatic hyperplasia / 中华全科医师杂志
Chinese Journal of General Practitioners
; (6): 50-52, 2016.
Article
en Zh
| WPRIM
| ID: wpr-489396
Biblioteca responsable:
WPRO
ABSTRACT
Thirty six patients aged 50-70 years with benign prostatic hyperplasia (BPH) received doxazosin and desmopressin treatment for 4 weeks.After treatment the International Prostate Symptom Scores (IPSS) and Quality of Life (QoL) scores of patients were significantly improved (17.4 ± 2.5 vs.11.8 ± 1.1 and 3.9 ±0.6 vs.1.8 ± 1.3,respectively;both P < 0.01).The nocturia frequency was decreased from 4.6±1.5 to 2.1±1.6 (P<0.01);nocturnal urine output from (564±73) to (348±45) ml (P<0.05);the hours of undisturbed sleep increased from (88.6 ± 17.5) min to (146.2 ± 12.8) min (P <0.05).There were no significant differences in serum levels of sodium,potassium and chlorine,and osmoticpressure before and after treatment.The results indicate that doxazosin combined with desmopressin is safe and effective for treatment of nocturia in patients with BPH.
Texto completo:
1
Base de datos:
WPRIM
Aspecto:
Patient_preference
Idioma:
Zh
Revista:
Chinese Journal of General Practitioners
Año:
2016
Tipo del documento:
Article