Literature Analysis of 646 Cases of Drug-induced Cardiovascular Diseases / 中国药房

ABSTRACT

OBJECTIVE:To find out the incidence and general patterns of drug-induced cardiovascular diseases and to guide rational use of drugs METHODS:By using literature metrological method 646 cases of drug-induced cardiovascular diseases which were reported in Chinese literatures in 1995～2000 were analysed RESULTS:Among those 646 cases,the incidence of arrhythmia was 59 8% The kinds of induced drugs were up to 155 and the most easily inducing one was cardiovascular system drug,which amounted to 37 2%(240/646) Propafenone had the highest incidence of all in inducing cardiovascular diseases(75 cases) There were 35(5 4%) fatal cases mainly caused by cardiovascular system drugs Most of the patients with drug-induced cardiovascular diseases were in middle-age and old age CONCLUSION:To reduce the rate of drug-induced diseases,cardiovascular system drugs should be rationally administrated and stictly supervised