Syndromic Approach to Parkinson's Disease: Role of Functional Imaging
Journal of Clinical Neurology
; : 83-91, 2006.
Article
en En
| WPRIM
| ID: wpr-52490
Biblioteca responsable:
WPRO
ABSTRACT
Current evidence from monogenic Parkinson's disease (PD) supports the view that PD is a clinical syndrome, rather than a single disease entity, and that the heterogeneity of PD indeed reflects different pathogenesis. Recent developments in functional imaging have enabled the in vivo assessment of cellular and molecular pathology of PD with respect to temporal and topographical patterns. We propose that this new technology will be useful for linking monogenic and sporadic PD, and thus, for classifying PD based on the pathogenesis. It will be also useful in clinico-genetic studies exploring susceptibility factors and at-risk groups, which are important for neuroprotective treatment when it becomes available.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Enfermedad de Parkinson
/
Patología
/
Características de la Población
/
Tomografía de Emisión de Positrones
/
Patología Molecular
Tipo de estudio:
Diagnostic_studies
Aspecto:
Determinantes_sociais_saude
Idioma:
En
Revista:
Journal of Clinical Neurology
Año:
2006
Tipo del documento:
Article