Peripheral Blood Lymphocytes Apoptosis and Expression of Fas and Bcl-2 in Patients with Secondary Syphilis / 中华皮肤科杂志
Chinese Journal of Dermatology
; (12)2003.
Article
en Zh
| WPRIM
| ID: wpr-526227
Biblioteca responsable:
WPRO
ABSTRACT
Objective To investigate the relationship between apoptosis of peripheral blood lymphocytes (PBLCs) and impaired immunity by assessing the apoptosis and expression of Fas and Bcl-2 in PBLCs of patients with secondary syphilis. Methods Flow cytometry (FCM) was used to detect PBLC apoptosis as well as Fas and Bcl-2 expression in 33 patients with secondary syphilis and 30 normal controls. Results The Fas expression on PBLCs and CD4+ cells was significantly higher in patients than that in controls (P 0.05). The apoptosis levels were significantly higher in PBLCs and CD4+ cells in patients than those in controls (P 0.05). In patients group, the apoptosis levels of both PBLCs and CD4+ cells had a positive correlation with the Fas expression (r = 0.68, P
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Dermatology
Año:
2003
Tipo del documento:
Article