Optimization of the Preparation Technology of Yuganning Patch by Orthogonal Experiment / 中国药房

ABSTRACT

OBJECTIVE: To optimizate the preparation process of Yuganning patch. METHODS: The preparation process of Yuganning patch was optimzied by orthogonal experiment with content of ointment, setting time, drying temperature and drying time as factors and the initial strength, peeling strength and degumming phenomenon as indexes. RESULTS: The optimum preparaition conditions were as follows the content of ointment was (7.6?0.1) g?100 cm-2; the setting time was 24 h; the drying temperature was 60 ℃ and drying time was 3.5 h. And this optimized process met quality control method. CONCLUSION: The optimized preparation process is feasible and the quality of the Yuganning patch is stable.