Transplantation of adipose derived mesenchymal stem cells for acute thoracolumbar disc disease with no deep pain perception in dogs
Journal of Veterinary Science
; : 123-126, 2016.
Article
en En
| WPRIM
| ID: wpr-56502
Biblioteca responsable:
WPRO
ABSTRACT
Thirty-four dogs with no deep pain perception due to acute thoracolumbar intervertebral disc disease underwent decompression surgery within 1 week of diagnosis. All dogs underwent hemilaminectomy. Adipose derived mesenchymal stem cells (AD-MSCs) were transplanted into the injured spinal cord parenchyma for the AD-MSCs transplant dogs. Long-term outcome was evaluated at the end of the follow-up period (> 6 months). AD-MSCs combination treatment showed better recovery outcomes compared to decompression surgery alone. These results indicate that this stem cell therapy is a potential therapeutic strategy to overcome the limitations of treatment for spinal cord injury in clinical medicine.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Tejido Adiposo
/
Enfermedad Aguda
/
Resultado del Tratamiento
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Descompresión Quirúrgica
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Trasplante de Células Madre Mesenquimatosas
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Enfermedades de los Perros
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Degeneración del Disco Intervertebral
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Percepción del Dolor
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Desplazamiento del Disco Intervertebral
Límite:
Animals
Idioma:
En
Revista:
Journal of Veterinary Science
Año:
2016
Tipo del documento:
Article