Effect of Compound Zaofan Pills on the Hemopoietic Function in Mice with Radiation Injury / 中药新药与临床药理

ABSTRACT

Objective To observe the effect of compound Zaofan Pills on the recovery of hemopoietic function in mice with radiation injury.Methods Three days after gastric infusion of compound Zaofan Pills 40 mg/mL (1 g/kg),the mice were treated with radiation of 60Co, 5 Gy per day. After 10 days of radiation, peripheral blood counting ,CFU-GM,BFU-E,CFU-E,CFU-S and the content of 3H-TDR integrated into DNA were tested.Results After treatment,compound Zaofan Pills increased the count of white blood cells, red blood cells and platelet, elevated CFU-GM,BFU-E and CFU-E and enhanced the content of 3H-TDR integrated into DNA (P 0.05).Conclusion Compound Zaofan Pills can promote the recovery of hemopoietic function in mice with radiation injury.