Specific Spectral Domain Optical Coherence Tomographic Findings of Oguchi Disease
Journal of the Korean Ophthalmological Society
; : 1041-1045, 2012.
Article
en Ko
| WPRIM
| ID: wpr-58032
Biblioteca responsable:
WPRO
ABSTRACT
PURPOSE: To report specific spectral domain OCT findings of Oguchi disease diagnosed with fundoscopic examination and electrophysiological study. CASE SUMMARY: A 14-year-old patient visited our clinic with a complaint of night blindness for ten years. Fundoscopic examination showed a golden-yellow fundus reflex. After three hours of dark adaptation, the fundus color returned to normal (Mizuo-Nakamura phenomenon). In full-field ERG, rod b-wave was not detectable. The a-wave amplitude in maximal combined response increased after three hours of dark adaptation, although the b-wave amplitude was similar to the amplitude before dark adaptation, demonstrating a negative waveform. In the spectral domain OCT images of the perifoveal area, no gap between the retinal pigment epithelium and the inner segment/outer segment (IS/OS) junction was detected before prolonged dark adaptation, and a highly reflective band was shown. However, the gap appeared after three hours of dark adaptation, and two highly reflective bands were detected in the OCT images. CONCLUSIONS: The characteristic OCT finding in addition to the specific fundoscopic finding and full-field ERG results may be useful to diagnose Oguchi disease.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Reflejo
/
Ceguera Nocturna
/
Adaptación a la Oscuridad
/
Tomografía de Coherencia Óptica
/
Electrorretinografía
/
Epitelio Pigmentado de la Retina
Tipo de estudio:
Diagnostic_studies
Límite:
Adolescent
/
Humans
Idioma:
Ko
Revista:
Journal of the Korean Ophthalmological Society
Año:
2012
Tipo del documento:
Article