Clinical Observation of Tripterygium Glycosides Combined with Mizolastine in the Treatment of Dermatitis and Eczema / 中国药房
China Pharmacy
; (12): 3805-3806,3807, 2016.
Article
en Zh
| WPRIM
| ID: wpr-605571
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVE:
To observe the efficacy and safety of tripterygium glycosides combined with mizolastine in the treatment of dermatitis and eczema.METHODS:
138 patients with dermatitis and eczema were randomly divided into control group (69 cases) and observation group (69 cases). Control group received Mizolastine sustained release tablet 10 mg,orally,once a day. Observation group additionally received Tripterygium glycosides tablet 20-30 mg,orally taking after a meal,3 times a day. All patients treated for 3 weeks,patients’life way remained unchanged during treatment. Clinical efficacy,total score of symptoms, IL-2,IL-6,CRP levels and the incidence of adverse reactions in 2 groups were observed.RESULTS:
The total effective rate in observation group was significantly higher than control group,with significant difference (P<0.01). After treatment,the total score of symptoms,IL-2,IL-6,CRP levels in 2 groups were significantly lower than before,and observation group was lower than control group,with significant differences(P<0.05 or P<0.01). The incidence of adverse reactions in observation group was significantly lower than control group,with significant difference (P<0.05).CONCLUSIONS:
Tripterygium glycosides combined with mizolastine shows better efficacy than mizolastine alone in the treatment of dermatitis and eczema,with better safety.
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
China Pharmacy
Año:
2016
Tipo del documento:
Article