Quality Standard for Juebi Capsules / 中国药师
China Pharmacist
; (12): 1662-1665, 2017.
Article
en Zh
| WPRIM
| ID: wpr-607395
Biblioteca responsable:
WPRO
ABSTRACT
Objective:To establish the quality standard for Juebi capsules. Methods:TLC was adopted to identify Paeoniae Ra-dix Rubra, Cyperi Rhizom and Cinnamomi Cortex; the contents of paeoniflorin and cinnamic aldehyde in Juebi capsules were deter-mined by HPLC with Wondasil C18 (250 mm × 4. 6 mm,5 μm) as the analytical column, the mobile phase was composed of methanol-0. 2% phosphoric acid solution with gradient elution, the flow rate was 1. 0 ml·min-1 ,the detection wavelengths were 230 nm and 290 nm, the column temperature was 40℃, and the volume injection was 10 μl. Results: The TLC spots were clear and well-separated without any negative interference;the calibration curves of paeoniflorin and Cinnamic aldehyde were in good linearity over the range of 0. 368-3. 680μg(r=0. 9999) and 0. 191-1. 914 μg(r=0. 9999), the average recovery was 101. 9 % and 99. 66%, and the RSD was 1. 90% and 2. 77% (n=6), respectively. Conclusion:The method is fast and accurate with good specificity, which can be used for the quality control of Juebi capsules.
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
China Pharmacist
Año:
2017
Tipo del documento:
Article