Diagnostic value of prostate imaging reporting and data system version 1 and 2 in detection of prostate cancer in transition zone / 中华放射学杂志
Chinese Journal of Radiology
; (12): 427-431, 2017.
Article
en Zh
| WPRIM
| ID: wpr-613551
Biblioteca responsable:
WPRO
ABSTRACT
Objective To evaluate the diagnostic value of prostate imaging reporting and data system version 1 (PI-RADS V1) and version 2 (PI-RADS V2) for detection of prostate cancer (PCa) in the transition zone (TZ).Methods Seventy-seven patients with suspicious lesions in TZ on mpMRI were scored according to the PI-RADS system (V1 and V2) before MR-TRUS fusion guided biopsy prospectively.In all of the patients with suspicious tumors,respectively at least one lesion with a PI-RADS V1 assessment category of ≥3,was selected for biopsy.Independent sample t test was used to compare scores of PI-RADS V1 and V2 between PCa and benign prostatic hyperplasia (BPH).The diagnostic performance of PI-RADS V 1 and V2 for detection of PCa in the transition zone was compared by analyzing ROC basing on the results of MR-TRUS fusion guided biopsy.Results A cohort of 77 patients was performed including 31 cases of PCa (32 cores) and 46 cases of BPH (51 cores).PCa (V11 1.50±2.79;V24.28±0.99) had significantly higher scores of both PI-RADS V1 and PI-RADS V2 than BPH(V17.51± 1.63;V2∶2.61 ±0.67) (P<0.05).Using a PI-RADS V1 score cut-off ≥ 11,sensitivity and specificity in group PCa and BPH were calculated,which were 68.8%(22/32) and 96.1%(49/51) with a area under curve of 0.869;using a PI-RADS V2 score cut-off ≥4,which were 75.0% (24/32) and 90.2% (46/51) with a area under curve of 0.888,respectively.Conclusions PI-RADS system can indicate the likelihood of PCa of suspicious lesions in TZ on Mp-MRI.PI-RADS V2 perform better than V 1 for the assessment of prostate cancer in TZ.
Texto completo:
1
Base de datos:
WPRIM
Tipo de estudio:
Diagnostic_studies
Idioma:
Zh
Revista:
Chinese Journal of Radiology
Año:
2017
Tipo del documento:
Article
Pais de publicación:
CHINA
/
CN
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REPUBLIC OF CHINA