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The relationship of LncRNA H19 with the occurrence and the carcinogenesis of OSF / 实用口腔医学杂志
Article en Zh | WPRIM | ID: wpr-619243
Biblioteca responsable: WPRO
ABSTRACT

Objective:

To study the significance of H19 gene in the progress from normal mucosa through oral submucous fibrosis (OSF) to carcinogenesis.

Methods:

Real-time fluorescent quantitative PCR technique was used to detect LncRNA H19 expression level in 12 cases of normal buccal mucosa tissue,33 cases of OSF buccal mucosa tissue and 31 cases of buccal carcinoma with OSF.

Results:

The relative expression levels of LncRNA H19 in normal buccal mucosa tissues,OSF buccal mucosa tissue and buccal carcinoma with OSF tissue were 1.17 ±0.37,3.44 ± 1.08 and 8.88 ± 1.78 respectively(between each 2 groups,P < 0.01).

Conclusion:

H19 may involve the occurrence and canceration of OSF.
Palabras clave
Texto completo: 1 Base de datos: WPRIM Idioma: Zh Revista: Journal of Practical Stomatology Año: 2017 Tipo del documento: Article Pais de publicación: CHINA / CN / REPUBLIC OF CHINA
Texto completo: 1 Base de datos: WPRIM Idioma: Zh Revista: Journal of Practical Stomatology Año: 2017 Tipo del documento: Article Pais de publicación: CHINA / CN / REPUBLIC OF CHINA