VALUATING THERAPY RESULTS AND ANALYSIS OF IMMEDIATE AND LONG-TERM TREATMENT TOXICITY IN A CLINICAL CASE SERIES OF NASOPHARYNGEAL CARCINOMA / 鼻咽癌杂志
Journal of NasoPharyngeal Carcinoma
; : 1-6, 2015.
Article
en En
| WPRIM
| ID: wpr-642417
Biblioteca responsable:
WPRO
ABSTRACT
Introduction and objective:
Nasopharyngeal carcinomas differ from other head and neck tumors. Patients have a higher rate of survival and thereby have a higher chance of presenting late toxicity, affecting their quality of life. We have tried to evaluate the most relevant late toxicities. Material andmethods:
We conducted a retrospective analysis in a series of 58 patients diagnosed with nasopharyngeal carcinoma between 1987 and 2014. The non-epithelial histological types were excluded from the study. We analyzed late toxicity and survival using SPSS version 19.Results:
We included 58 patients, 93,1% of whom presented locally advanced disease at the time of diagnosis. The predominant subtype was found to be undifferentiated carcinoma. The treatment response rate was 91,2% (75,4% complete response and 15,8% partial response). The relapse rate was 35,1% (35% local relapse and 65% systemic relapse). The median disease-free survival was 150 months and the mean global survival was 224 months (168-279).Conclusions:
Nasopharyngeal carcinoma is usually diagnosed in a locally advanced stage. Treatment is based on the use of chemotherapy and radiotherapy, obtaining a high response rate. Currently, there is large group of survivors, whose quality of life is severely affected by late toxicity.
Texto completo:
1
Base de datos:
WPRIM
Aspecto:
Patient_preference
Idioma:
En
Revista:
Journal of NasoPharyngeal Carcinoma
Año:
2015
Tipo del documento:
Article
Pais de publicación:
CHINA
/
CN
/
REPUBLIC OF CHINA