Comparison of Methods for Collecting Saliva for Pepsin Detection in Patients with Laryngopharyngeal Reflux / 대한이비인후과학회지
Korean Journal of Otolaryngology - Head and Neck Surgery
; : 570-574, 2017.
Article
en En
| WPRIM
| ID: wpr-651303
Biblioteca responsable:
WPRO
ABSTRACT
BACKGROUND AND OBJECTIVES:
To compare the simple spitting method and the Salivette® method of collecting saliva for detecting pepsin in patients with laryngopharyngeal reflux disease (LPRD). SUBJECTS ANDMETHOD:
Thirty-two patients diagnosed with LPRD by 24 hour multichannel intraluminal impedance and pH monitoring were enrolled prospectively. The amounts of pepsin in saliva determined by the simple spitting method and the Salivette® method were compared.RESULTS:
Simple spitting showed higher sensitivity, specificity, accuracy, positive predictive value and negative predictive value. There was no statistically significant difference between the amount of pepsin detected by simple spitting (10.07±11.68 ng/mL) versus that detected using the Salivette® method (7.09±7.27 ng/mL) (p=0.258).CONCLUSIONS:
The simple spitting method has higher sensitivity, specificity and accuracy than the Salivette® method for detecting pepsin in patients with LPRD.Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Saliva
/
Estudios Prospectivos
/
Pepsina A
/
Sensibilidad y Especificidad
/
Impedancia Eléctrica
/
Reflujo Laringofaríngeo
/
Concentración de Iones de Hidrógeno
/
Métodos
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
Límite:
Humans
Idioma:
En
Revista:
Korean Journal of Otolaryngology - Head and Neck Surgery
Año:
2017
Tipo del documento:
Article