Recent advances in cellular scaffolds for retinal pigment epithelium cell transplantation / 中华眼底病杂志
Chinese Journal of Ocular Fundus Diseases
; (6): 655-658, 2017.
Article
en Zh
| WPRIM
| ID: wpr-668945
Biblioteca responsable:
WPRO
ABSTRACT
Replacement of diseased retinal pigment epithelium (RPE) cells with healthy RPE cells by transplantation is one option to treat several retinal degenerative diseases including age-related macular degeneration,which are caused by RPE loss and dysfunction.A cellular scaffold as a carrier for transplanted cells,may hold immense promise for facilitating cell migration and promoting the integration of RPE ceils into the host environment.Scaffolds can be prepared from a variety of natural and synthetic materials.Strategies,such as surface modification and structure adjustment,can improve the biomimetic properties of the scaffolds,optimize cell attachment and cellular function following transplantation and lay a foundation of clinical application in the future.
Texto completo:
1
Base de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Ocular Fundus Diseases
Año:
2017
Tipo del documento:
Article