Endocrinologic Complications after Traumatic Brain Injury
Brain & Neurorehabilitation
; : 52-57, 2012.
Article
en En
| WPRIM
| ID: wpr-68134
Biblioteca responsable:
WPRO
ABSTRACT
The endocrinologic complications such as adrenal insufficiency and hypopituitarism are common after traumatic brain injury (TBI) portending poor rehabilitation outcome. Anterior pituitary dysfunction presents as hypothyroidism, hypogonadism, growth hormone deficiency, adrenal insufficiency and hyperprolactinemia, whereas posterior pituitary dysfunction includes syndrome of inappropriate antidiuretic hormone and central diabetes insipidus. Careful history taking and physical examination are essential to detect these abnormalities early. Laboratory tests such as serum/urine sodium and osmolality, thyroid hormone, testosterone, estradiol, cortisol, prolactin, growth hormone or IGF-1 are also necessary. Screening of endocrinologic functions is recommended especially in patients with moderate or severe TBI, skull base fracture or diffuse axonal injury 3 to 6 months after injury. Further studies are needed to reveal the effect of early correction of endocrinologic abnormality on long-term functional outcome.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Concentración Osmolar
/
Examen Físico
/
Prolactina
/
Sodio
/
Testosterona
/
Glándula Tiroides
/
Lesiones Encefálicas
/
Hiperprolactinemia
/
Factor I del Crecimiento Similar a la Insulina
/
Hidrocortisona
Tipo de estudio:
Prognostic_studies
/
Screening_studies
Límite:
Humans
Idioma:
En
Revista:
Brain & Neurorehabilitation
Año:
2012
Tipo del documento:
Article