Effects of pinacidil on intracellular free calcium concentration of cultured neonatal rat cardiomyocytes during hypoxia/reoxygenation / 医学研究生学报
Journal of Medical Postgraduates
; (12)2003.
Article
en Zh
| WPRIM
| ID: wpr-684220
Biblioteca responsable:
WPRO
ABSTRACT
Objectives: To examine effects of pinacidil on intracellular free calcium concentration of cardiomyocytes during hypoxia/reoxygenation. Methods:A cell culture model of neonatal rat cardiac myocytes was used. There were three groups, including control group, hypoxia/reoxygenation group and pinacidil group. Confocal microscope was used with Fluo 3/AM as calcium indicator to detect changes of intracellular free calcium concentration. Results:The intracellular fluoresence intensity of singular cardiomyocyte in hypoxia/reoxygenation group was significantly higher than that of the controls( P
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
Journal of Medical Postgraduates
Año:
2003
Tipo del documento:
Article