The Impact of Metabolic Syndrome on Post-operative Bleeding and In-hospital Prognosis in Patients With Coronary Artery Bypass Grafting / 中国循环杂志

ABSTRACT

Objective: To explore the impact of metabolic syndrome (MS) on post-operative bleeding and in-hospital prognosis in patients with coronary artery bypass grafting (CABG). Methods: A total of 542 patients received CABG in Fuwai hospital from 2012-06 to 2012-09 were enrolled. Based on existing MS, the patients were divided into 2 groups MS group, n=223 and Non-MS group, n=319. The amounts of 24 h post-operative bleeding and total bleeding were compared between 2 groups; the impact of MS for in-hospital prognosis was studied. Results: Compared with Non-MS group, MS group had the higher ratio of female patients (17.9％ vs 29.1％), P=0.002; the lower ratio of patients with plasma transfusion during operation and post-operation (20.7％ vs 12.6％), P=0.015 and the higher ratio of patients with zero plasma transfusion during operation and post-operation (79.3％ vs 87.5％), P=0.015. The median of 24h post-operative bleeding amount in MS group was lower [710.00(530.00, 950.00)ml vs 580.00(430.00, 790.00)ml, P<0.001]. The ratio of patients with total post-operative bleeding amount from (0-500)ml and (501-1000)ml was higher in MS group(4.4％ vs 10.8％, P=0.006;41.1％ vs 53.4％, P=0.005,respectively). MS group had the lower ratios of patients with 24 h post-operative bleeding amount>1000 ml, P=0.004, with total post-operative bleeding amount from (1001-2000) ml, P=0.001 and with total post-operative bleeding amount>2001 ml,P=0.044. Conclusion: MS patients had the lower amounts of peri-operative plasma transfusion and post-operative bleeding in CABG;while it had no impact on in-hospital prognosis.