Genotypes and epidemiological characteristics of Noroviruses in Shenzhen during the winter of 2017 / 中华微生物学和免疫学杂志
Chinese Journal of Microbiology and Immunology
; (12): 725-730, 2018.
Article
en Zh
| WPRIM
| ID: wpr-711446
Biblioteca responsable:
WPRO
ABSTRACT
Objective To study the genotypes, epidemiological characteristics and homology of Noroviruses (NoV) circulating in Shenzhen in the winter of 2017. Methods RT-PCR was performed using Nov-specific primers after extracting viral genome from 313 fecal samples. Positive RT-PCR products were then sequenced. Phylogenetic trees were constructed based upon the gene sequences of isolated and reference NoV strains using Mega 4. 1 and Clustal W software. Results There were 26 NoV-positive samples and all belonged to G Ⅱ. 4 subtype. These strains shared high homologies with G Ⅱ. 4 ( KY407156), G Ⅱ. 4 (KY580757) and GⅡ. 4 (KX372682). Phylogenetic analysis also suggested that 88. 46% of them had a lower homology with the NoV strains isolated in the same area in recent years and 46. 15% were different from the epidemic strains in other provinces of China. Conclusion NoV GⅡ. 4 was the epidemic strain in Shenzhen during the winter of 2017. More attention should be paid to it from the local public health authori-ties considering its owned characteristics in epidemic and homology.
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Microbiology and Immunology
Año:
2018
Tipo del documento:
Article