Epidemiologic Evidence of and Potential Mechanisms by Which Second-Hand Smoke Causes Predisposition to Latent and Active Tuberculosis
Immune Network
; : e22-2018.
Article
en En
| WPRIM
| ID: wpr-715076
Biblioteca responsable:
WPRO
ABSTRACT
Many studies have linked cigarette smoke (CS) exposure and tuberculosis (TB) infection and disease although much fewer have studied second-hand smoke (SHS) exposure. Our goal is to review the epidemiologic link between SHS and TB as well as to summarize the effects SHS and direct CS on various immune cells relevant for TB. PubMed searches were performed using the key words “tuberculosis” with “cigarette,”“tobacco,” or “second-hand smoke.” The bibliography of relevant papers were examined for additional relevant publications. Relatively few studies associate SHS exposure with TB infection and active disease. Both SHS and direct CS can alter various components of host immunity resulting in increased vulnerability to TB. While the epidemiologic link of these 2 health maladies is robust, more definitive, mechanistic studies are required to prove that SHS and direct CS actually cause increased susceptibility to TB.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Humo
/
Contaminación por Humo de Tabaco
/
Tuberculosis
/
Fumar
/
Productos de Tabaco
/
Mycobacterium tuberculosis
Tipo de estudio:
Etiology_studies
Aspecto:
Implementation_research
Idioma:
En
Revista:
Immune Network
Año:
2018
Tipo del documento:
Article