Liquid Biopsy: Current Status and Future Perspective in Gastric Cancer and Helicobacter Infection / 대한Helicobacter연구학회지
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
; : 150-156, 2018.
Article
en Ko
| WPRIM
| ID: wpr-716953
Biblioteca responsable:
WPRO
ABSTRACT
Precision medicine stands for 4Ps - precise, preventive, participatory, and personal; in which “precision” is important because the current modern medicine starts from “trial and error,” and “one does not fit all”. Current targeted therapies for cancer have changed treatment approaches and led the precision medicine; however, clinical use of liquid biopsy, using blood or other liquid specimens to characterize circulating tumor cells (CTC) or tumor genes instead of biopsies of tumor tissues, still awaits availability of more information regarding non-invasive cancer detection and characterization, prediction of treatment response, monitoring the disease course and relapse possibilities, identification of mechanisms of drug resistance, and newer pathogenesis. In this review, we will introduce the basic concept of CTC, circulating cell free DNA, and exosomes and their possible application for gastric cancer relevant with Helicobacter pylori infection.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Recurrencia
/
Neoplasias Gástricas
/
Biopsia
/
ADN
/
Resistencia a Medicamentos
/
Helicobacter pylori
/
Infecciones por Helicobacter
/
Helicobacter
/
Historia Moderna 1601-
/
Exosomas
Tipo de estudio:
Prognostic_studies
Límite:
Humans
Idioma:
Ko
Revista:
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Año:
2018
Tipo del documento:
Article