A Case of Clozapine-induced Corneal and Lenticular Pigmentation
Journal of the Korean Ophthalmological Society
; : 276-279, 2019.
Article
en Ko
| WPRIM
| ID: wpr-738608
Biblioteca responsable:
WPRO
ABSTRACT
PURPOSE:
To report a case of corneal and lenticular pigmentation after prolonged clozapine therapy. CASESUMMARY:
A 56-year-old male visited our hospital with a progressive decline in vision that affected both eyes. He had a history of schizophrenia. He was being treated with 200 mg clozapine and 1 mg lorazepam daily, and had been treated with clozapine for 5 years. At the first visit, his best-corrected-visual acuity was 20/32 in both eyes. Slit lamp examination of the corneas showed bright, fine, grayish-brown deposits on the endothelium, and on dilation, bilateral central stellate opacity of the anterior portion of the lens capsule was revealed.CONCLUSIONS:
Clozapine may induce corneal and lenticular pigmentation and thus may lead to a decline in vision. Patients on long-term clozapine therapy should be considered for regular ophthalmic review.Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Esquizofrenia
/
Pigmentación
/
Clozapina
/
Córnea
/
Endotelio
/
Lámpara de Hendidura
/
Lorazepam
Límite:
Humans
/
Male
Idioma:
Ko
Revista:
Journal of the Korean Ophthalmological Society
Año:
2019
Tipo del documento:
Article