The expression of FasL and ICAM-1 on the HEVs in the hypertrophic tonsils / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
; (24): 700-702, 2007.
Article
en Zh
| WPRIM
| ID: wpr-748359
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVE@#To investigate the expression of FasL and ICAM-1 on the HEVs in the hypertrophic tonsils and its clinical significance.@*METHOD@#Under the light microscopy, HE and immunohistochemistry methods were used to show the morphology of HEVs, the number of T, B lymphocytes, the expression intensity of FasL and ICAM-1 in 17 patients with the idiopathic tonsillar hypertrophy (ITH) and in 20 patients with the chronic hypertrophic tonsillitis (CHT).@*RESULT@#The expression intensity of ICAM-1 on the tonsillar HEVs in ITH group was significantly lower than that in CTH group (P < 0.05), but the intensity of FasL in ITH group was significantly higher than that in CHT group (P < 0.05).@*CONCLUSION@#FasL and ICAM-1 expression in the tonsillar HEVs contribute to the CHT and ITH. The former mainly makes IHT developed, and the latter promotes the process of the inflammation.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Patología
/
Tonsila Palatina
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Vénulas
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Linfocitos B
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Linfocitos T
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Tonsilitis
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Molécula 1 de Adhesión Intercelular
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Endotelio
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Alergia e Inmunología
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Proteína Ligando Fas
Límite:
Adolescent
/
Child
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Child, preschool
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Female
/
Humans
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Male
Idioma:
Zh
Revista:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Año:
2007
Tipo del documento:
Article