Content of CD4+ CD25+ regulatory T cells in peripheral blood lymphocytes in patients with allergic rhinitis / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
; (24): 354-359, 2011.
Artículo
en Chino
| WPRIM (Pacífico Occidental)
| ID: wpr-748465
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVE@#To investigate the change of CD4- CD25 regulatory T cells (Tregs) of peripheral blood in allergic rhinitis (AR) patients.@*METHOD@#T lymphocytes of twenty AR patients and eight healthy subjects were separated and the flow cytometry was used to measure the percentage of CD4+ CD25+ Treg.@*RESULT@#Compared with control group, the percentage of Treg and CD4- CD25high Tregs of AR patients was decreased significantly (P < 0.05).@*CONCLUSION@#The proportion of CD4+ CD25+ Tregs decreased in AR patients conspicuously, which might be one of the pathogenesis of AR.
Texto completo:
Disponible
Base de datos:
WPRIM (Pacífico Occidental)
Asunto principal:
Sangre
/
Estudios de Casos y Controles
/
Rinitis Alérgica Perenne
/
Linfocitos T Reguladores
/
Alergia e Inmunología
/
Subunidad alfa del Receptor de Interleucina-2
/
Citometría de Flujo
/
Metabolismo
Tipo de estudio:
Estudio observacional
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Año:
2011
Tipo del documento:
Artículo
