A case of hemophagocytic lymphohistiocytosis caused by an Epstein-Barr virus infection, presenting with unremitting fever and rash
Pediatric Emergency Medicine Journal
; : 26-30, 2019.
Article
en Ko
| WPRIM
| ID: wpr-760849
Biblioteca responsable:
WPRO
ABSTRACT
Hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory syndrome caused by excessive activation of lymphocytes and macrophages, leading to cytokine storm. Infection-associated HLH is most common, and Epstein-Barr virus is the leading triggers. Quick diagnosis is essential for starting the treatment before irreversible damage. We report a case of 16-year-old boy who presented with unremitted fever, jaundice, and erythematous maculopapular rash all over the body. Investigations showed thrombocytopenia, hyperferritinemia, hypertriglycemia, and the bone marrow biopsy showed hemophagocytosis. Epstein-Barr virus antibody was positive. He responded to chemotherapy as per the HLH-2004 protocol and supportive treatment, and was discharged without complication on day 17.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Trombocitopenia
/
Biopsia
/
Médula Ósea
/
Linfocitos
/
Herpesvirus Humano 4
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Infecciones por Virus de Epstein-Barr
/
Diagnóstico
/
Quimioterapia
/
Linfohistiocitosis Hemofagocítica
/
Exantema
Tipo de estudio:
Diagnostic_studies
/
Guideline
Límite:
Adolescent
/
Humans
/
Male
Idioma:
Ko
Revista:
Pediatric Emergency Medicine Journal
Año:
2019
Tipo del documento:
Article