Identification of Radioactive Iodine Refractory Differentiated Thyroid Cancer / 전남의대학술지
Chonnam Medical Journal
; : 127-135, 2019.
Article
en En
| WPRIM
| ID: wpr-763293
Biblioteca responsable:
WPRO
ABSTRACT
Most differentiated thyroid cancer (DTC) patients have an excellent prognosis. However, about one-third of DTC patients with recurrent or metastatic disease lose the hallmark of specific iodine uptake initially or gradually and acquire radioactive iodine-refractory DTC (RAIR-DTC) with poor prognosis. Due to the potentially severe complications from unnecessarily repeated RAI therapy and encouraging progress of multiple targeted drugs for advanced RAIR-DTC patients, it has become crucial to identify RAIR-DTC early. In this review, we focus on the progress and controversies regarding the defining of RAIR-DTC, further with subsistent approaches and promising molecular nuclear medicine imaging in identifying RAIR-DTC, which may shed light on the proper management methodsof such patients.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Pronóstico
/
Glándula Tiroides
/
Neoplasias de la Tiroides
/
Imagen Molecular
/
Yodo
/
Radioisótopos de Yodo
/
Medicina Nuclear
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
Chonnam Medical Journal
Año:
2019
Tipo del documento:
Article