A new eudesmane type sesquiterpene from cultivated Clerodendranthus spicatus in Hainan / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 95-99, 2019.
Article
en Zh
| WPRIM
| ID: wpr-771512
Biblioteca responsable:
WPRO
ABSTRACT
Six compounds were isolated from the aerial part of cultivated Clerodendranthus spicatus in Hainan with various chromatographic techniques,and their structures were determined as1-dehydroxy-1-oxo-rupestrinol(1),N-trans-feruloyltyramine(2),methyl 3,4-dihydroxyphenyllactate(3),caffein acid(4),methyl caffeate(5) and ethyl caffeate(6),via analysis of physicochemical properties and spectroscopic evidence.Compound 1 was a new compound,while compounds 2 and 3 were isolated from C.spicatus for the first time.Biological activity results showed that compounds 2-4 exhibited α-glucosidase inhibitory activity with different inhibition ratio.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Farmacología
/
Estructura Molecular
/
Química
/
China
/
Lamiaceae
/
Sesquiterpenos de Eudesmano
/
Fitoquímicos
/
Inhibidores de Glicósido Hidrolasas
País/Región como asunto:
Asia
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Año:
2019
Tipo del documento:
Article