Tight junctions-associated proteins:a novel therapeutic target for cholestatic liver injury / 中国药科大学学报
Journal of China Pharmaceutical University
; (6): 143-151, 2019.
Article
en Zh
| WPRIM
| ID: wpr-804543
Biblioteca responsable:
WPRO
ABSTRACT
@#The occurrence of cholestatic liver injury is accompanied by the alterations of hepatocyte polarization and bile acid homeostasis. Located in epithelial cells, tight junctions(TJs)are a special barrier structure which are important in maintaining permeability and bile acid homeostasis. Based on the fully analysis and discussion of TJs, the latest therapeutic drugs for cholestasis were summaried, which may provide new perspectives and potential therapeutic agents for the treatment of cholestatic liver injury.
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
Journal of China Pharmaceutical University
Año:
2019
Tipo del documento:
Article