Protein expression and receptor binding specificity of porcine P19 rotavirus VP8* / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
; (6): 89-92, 2018.
Article
en Zh
| WPRIM
| ID: wpr-805917
Biblioteca responsable:
WPRO
ABSTRACT
Objective@#To explore the receptor binding specificity of VP8* protein of porcine P[19] rotaviruses (RVs) with oligosaccharides.@*Methods@#The porcine P[19] VP8* protein was expressed and purified. The receptor binding specificity of P[19] VP8* was analyzed by oligosaccharide binding and saliva binding assay.@*Results@#The P[19] VP8* protein showed significant binding to mucin cores, especially mucin core 2.@*Conclusions@#Mucin core 2 may be a potential receptor for the porcine P[19] RV, which provides certain basis for the study of virus infection mechanism and RV surveillance.
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Experimental and Clinical Virology
Año:
2018
Tipo del documento:
Article