A female adnexal tumor of probable Wolffian origin showing positive O-6-methylguanine-DNA methyltransferase methylation
Obstetrics & Gynecology Science
; : 328-332, 2016.
Article
en En
| WPRIM
| ID: wpr-81072
Biblioteca responsable:
WPRO
ABSTRACT
Female adnexal tumor of probable Wolffian origin (FATWO) is a rare disease entity that arises from the mesonephric duct system. FATWO is different than other gynecological cancers in terms of embryology. Here, we describe the case of a 52-year-old woman with malignant FATWO. The patient underwent explorative laparotomy and surgical staging after a frozen section revealed malignancy. Detailed examination of the pathologic findings were consistent with FATWO. Counseling and further testing were provided to the patient to assess the risk of germline mutation and epigenetic change. An O-6-methylguanine-DNA methyltransferase gene methylation test was positive, and all other tests were normal. This is the first study to report a case of O-6-methylguanine-DNA methyltransferase methylation with FATWO in Korea.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Conductos Mesonéfricos
/
Embriología
/
Mutación de Línea Germinal
/
Consejo
/
Enfermedades Raras
/
Epigénesis Genética
/
Epigenómica
/
Secciones por Congelación
/
Corea (Geográfico)
/
Laparotomía
Límite:
Female
/
Humans
País/Región como asunto:
Asia
Idioma:
En
Revista:
Obstetrics & Gynecology Science
Año:
2016
Tipo del documento:
Article