Visfatin level after laparoscopic Roux-en-Y gastric bypass surgery in patients with Type 2 diabetes / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
; (12): 258-261, 2013.
Article
en Zh
| WPRIM
| ID: wpr-814879
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVE@#To investigate the change in serum visfatin level after laparoscopic Roux-en-Y gastric bypass surgery in patients with Type 2 diabetes mellitus (T2DM) and to explore the relationship between visfatin insulin resistance and diabetes.@*METHODS@#Thirty-three patients with Type 2 diabetes were studied before and after the gastric bypass surgery. The level of fasting serum visfatin was measured by enzyme-linked immunosorbent assay. Fasting plasma glucose (FPG), glycated hemoglobin (HbA1c) and fasting insulin (FINS) were measured before and after the gastric bypass surgery.@*RESULTS@#Compared with before the operation, the indicators of HbA1c, FINS, and insulin resistance index (HOMA-IR) were decreased after the laparoscopic Roux-en-Y gastric bypass surgery. The body mass index (BMI) [(24.53 ± 0.62) kg/m² vs (26.71 ± 0.69) kg/m2] was decreased, with significant difference (P<0.001). The serum visfatin level [(9.79 ± 0.64) ng/mL] was significantly lower than before the operation [(38.24 ± 5.32) ng/mL], with significant difference (P<0.001).@*CONCLUSION@#Serum level of visfatin is decreased in T2DM patients who undergo gastric bypass surgry, reflecting an improvement in insulin resistance and diabetes.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Periodo Posoperatorio
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Cirugía General
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Sangre
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Resistencia a la Insulina
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Derivación Gástrica
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Laparoscopía
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Diabetes Mellitus Tipo 2
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Nicotinamida Fosforribosiltransferasa
Límite:
Female
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Humans
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Male
Idioma:
Zh
Revista:
Journal of Central South University(Medical Sciences)
Año:
2013
Tipo del documento:
Article