Study on the secondary metabolites of grasshopper-derived fungi Arthrinium sp. NF2410 / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
; (6): 957-960, 2020.
Article
en En
| WPRIM
| ID: wpr-881042
Biblioteca responsable:
WPRO
ABSTRACT
Two new 2-carboxymethyl-3-hexyl-maleic anhydride derivatives, arthrianhydride A (1) and B (2), along with three known compounds 3-5, were isolated from the fermentation broth of a grasshopper-associated fungus Arthrinium sp. NF2410. The structures of new compounds 1 and 2 were determined based on the analysis of the HR-ESI-MS and NMR spectroscopic data. Furthermore, compounds 1 and 2 were evaluated on inhibitory activity against the enzyme SHP2 and both of them showed moderate inhibitory activity against SHP2.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Productos Biológicos
/
Estructura Molecular
/
Inhibidores Enzimáticos
/
Proteína Tirosina Fosfatasa no Receptora Tipo 11
/
Metabolismo Secundario
/
Hongos
/
Saltamontes
/
Anhídridos
Límite:
Animals
Idioma:
En
Revista:
Chinese Journal of Natural Medicines (English Ed.)
Año:
2020
Tipo del documento:
Article
Pais de publicación:
CHINA
/
CN
/
REPUBLIC OF CHINA