Electromagnetic field exposure as a plausible approach to enhance the proliferation and differentiation of mesenchymal stem cells in clinically relevant scenarios / 浙江大学学报(英文版)(B辑:生物医学和生物技术)
Journal of Zhejiang University. Science. B
; (12): 42-57, 2022.
Article
en En
| WPRIM
| ID: wpr-929038
Biblioteca responsable:
WPRO
ABSTRACT
Mesenchymal stem/stromal cell (MSC)-based therapy has been regarded as one of the most revolutionary breakthroughs in the history of modern medicine owing to its myriad of immunoregulatory and regenerative properties. With the rapid progress in the fields of osteo- and musculoskeletal therapies, the demand for MSC-based treatment modalities is becoming increasingly prominent. In this endeavor, researchers around the world have devised new and innovative techniques to support the proliferation of MSCs while minimizing the loss of hallmark features of stem cells. One such example is electromagnetic field (EMF) exposure, which is an alternative approach with promising potential. In this review, we present a critical discourse on the efficiency, practicability, and limitations of some of the relevant methods, with insurmountable evidence backing the implementation of EMF as a feasible strategy for the clinically relevant expansion of MSCs.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Transducción de Señal
/
Diferenciación Celular
/
Proliferación Celular
/
Campos Electromagnéticos
/
Células Madre Mesenquimatosas
Idioma:
En
Revista:
Journal of Zhejiang University. Science. B
Año:
2022
Tipo del documento:
Article