Circadian rhythm in prostate cancer: time to take notice of the clock / 亚洲男科学杂志(英文版)
Asian Journal of Andrology
; (6): 184-191, 2023.
Article
en En
| WPRIM
| ID: wpr-971016
Biblioteca responsable:
WPRO
ABSTRACT
The circadian clock is an evolutionary molecular product that is associated with better adaptation to changes in the external environment. Disruption of the circadian rhythm plays a critical role in tumorigenesis of many kinds of cancers, including prostate cancer (PCa). Integrating circadian rhythm into PCa research not only brings a closer understanding of the mechanisms of PCa but also provides new and effective options for the precise treatment of patients with PCa. This review begins with patterns of the circadian clock, highlights the role of the disruption of circadian rhythms in PCa at the epidemiological and molecular levels, and discusses possible new approaches to PCa therapy that target the circadian clock.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Neoplasias de la Próstata
/
Ritmo Circadiano
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Relojes Circadianos
/
Carcinogénesis
Límite:
Humans
/
Male
Idioma:
En
Revista:
Asian Journal of Andrology
Año:
2023
Tipo del documento:
Article