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Advances in neutrophil extracellular traps in bronchopulmonary dysplasia / 国际儿科学杂志
Article en Zh | WPRIM | ID: wpr-989077
Biblioteca responsable: WPRO
ABSTRACT
Due to the development of neonatal intensive care, the survival rate of very preterm infants and very low birth weight infants has been significantly improved, and the incidence of bronchopulmonary dysplasia (BPD) has been obviously increasing year by year.The pathogenesis of BPD has not been clear, it is considered that inflammation is an important link in the occurrence and development of BPD at present.Neutrophils can use their neutrophil extracellular traps (NETs) to capture and kill pathogens and reduce inflammation, but excessive formation of NETs is easy to induce inflammatory imbalance, so as to damage normal cells or tissues and participate in the pathophysiological process of BPD.This paper reviews the structure, formation, function and regulatory role of NETs in BPD, and the targeted treatment strategies and potential research directions of NETs in BPD.
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Texto completo: 1 Base de datos: WPRIM Idioma: Zh Revista: International Journal of Pediatrics Año: 2023 Tipo del documento: Article
Texto completo: 1 Base de datos: WPRIM Idioma: Zh Revista: International Journal of Pediatrics Año: 2023 Tipo del documento: Article