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Choice of first antihypertensive--are existing guidelines ignored?
Okechukwu, Ifeanyi; Mahmud, Azra; Bennett, Kathleen; Feely, John.
Affiliation
  • Okechukwu I; Department of Pharmacology & Therapeutics, Trinity College Centre for Health Sciences, St James's Hospital Dublin 8, Ireland.
Br J Clin Pharmacol ; 64(6): 722-5, 2007 Dec.
Article in En | MEDLINE | ID: mdl-17953721
ABSTRACT

AIMS:

To determine adherence to hypertension guidelines in relation to age and diabetes.

METHODS:

The Irish HSE-PCRS prescribing database identified patients initiating antihypertensive monotherapy in 2005. Logistic regression predicted the likelihood of therapy according to guidelines.

RESULTS:

The odds ratio (OR) of receiving therapies according to the guideline recommendations in those <55 years vs. > or =55 years was 1.31 (95% CI 1.26, 1.37). Diabetics were more likely than nondiabetics to receive antihypertensives other than beta-adrenoceptor blockers (OR 2.97, 95% CI 2.74, 3.21).

CONCLUSIONS:

Our findings show some adherence to the guidelines in relation to age but selective prescribing of antihypertensives for diabetics.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Choice Behavior / Practice Guidelines as Topic / Guideline Adherence / Antihypertensive Agents Type of study: Guideline / Prognostic_studies Limits: Humans Language: En Journal: Br J Clin Pharmacol Year: 2007 Document type: Article Affiliation country: Publication country: ENGLAND / ESCOCIA / GB / GREAT BRITAIN / INGLATERRA / REINO UNIDO / SCOTLAND / UK / UNITED KINGDOM

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Choice Behavior / Practice Guidelines as Topic / Guideline Adherence / Antihypertensive Agents Type of study: Guideline / Prognostic_studies Limits: Humans Language: En Journal: Br J Clin Pharmacol Year: 2007 Document type: Article Affiliation country: Publication country: ENGLAND / ESCOCIA / GB / GREAT BRITAIN / INGLATERRA / REINO UNIDO / SCOTLAND / UK / UNITED KINGDOM