Design, synthesis, and structure-activity relationship of tropane muscarinic acetylcholine receptor antagonists.

Lainé, Dramane I; Wan, Zehong; Yan, Hongxing; Zhu, Chongjie; Xie, Haibo; Fu, Wei; Busch-Petersen, Jakob; Neipp, Christopher; Davis, Roderick; Widdowson, Katherine L; Blaney, Frank E; Foley, James; Bacon, Alicia M; Webb, Edward F; Luttmann, Mark A; Burman, Miriam; Sarau, Henry M; Salmon, Michael; Palovich, Michael R; Belmonte, Kristen

Lainé, Dramane I; Wan, Zehong; Yan, Hongxing; Zhu, Chongjie; Xie, Haibo; Fu, Wei; Busch-Petersen, Jakob; Neipp, Christopher; Davis, Roderick; Widdowson, Katherine L; Blaney, Frank E; Foley, James; Bacon, Alicia M; Webb, Edward F; Luttmann, Mark A; Burman, Miriam; Sarau, Henry M; Salmon, Michael; Palovich, Michael R; Belmonte, Kristen.

Affiliation

Lainé DI; Respiratory CEDD, GlaxoSmithKline, 709 Swedeland Road, P.O. Box 1539, King of Prussia, PA 19406-0939, USA. dramane.i.laine@gsk.com

J Med Chem ; 52(16): 5241-52, 2009 Aug 27.

Article in En | MEDLINE | ID: mdl-19630384

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tropanes / Biphenyl Compounds / Muscarinic Antagonists / Bridged Bicyclo Compounds, Heterocyclic Type of study: Prognostic_studies Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2009 Document type: Article Affiliation country:

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