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A novel metabolite of antituberculosis therapy demonstrates host activation of isoniazid and formation of the isoniazid-NAD+ adduct.
Mahapatra, Sebabrata; Woolhiser, Lisa K; Lenaerts, Anne J; Johnson, John L; Eisenach, Kathleen D; Joloba, Moses L; Boom, W Henry; Belisle, John T.
Affiliation
  • Mahapatra S; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523, USA. sebabrata.mahapatra@colostate.edu
Antimicrob Agents Chemother ; 56(1): 28-35, 2012 Jan.
Article in En | MEDLINE | ID: mdl-22037847
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tuberculosis, Pulmonary / Isoniazid / Mycobacterium tuberculosis / NAD / Antitubercular Agents Limits: Animals / Female / Humans Language: En Journal: Antimicrob Agents Chemother Year: 2012 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tuberculosis, Pulmonary / Isoniazid / Mycobacterium tuberculosis / NAD / Antitubercular Agents Limits: Animals / Female / Humans Language: En Journal: Antimicrob Agents Chemother Year: 2012 Document type: Article Affiliation country: Country of publication: