Viral etiology of influenza-like illnesses in Cameroon, January-December 2009.
J Infect Dis
; 206 Suppl 1: S29-35, 2012 Dec 15.
Article
in En
| MEDLINE
| ID: mdl-23169968
ABSTRACT
BACKGROUND:
No information is available on the viral etiology of upper respiratory tract infections in Cameroon.METHODS:
We prospectively enrolled outpatients with influenza-like illness (ILI) presenting at 14 sentinel clinics located across the country from January through December 2009. The specimens were tested using real-time and multiplex reverse-transcription polymerase chain reaction methods for the detection of 15 RNA respiratory viruses.RESULTS:
We detected at least 1 respiratory virus in 365 of 561 specimens (65.1%). Overall, influenza virus was the most commonly detected virus (28.2% of specimens), followed by human rhinovirus (17.8%); parainfluenza virus (PIV) types 1-4 (7.5%); enterovirus (5.9%); respiratory syncytial virus (RSV; 5.7%); human coronavirus (HCoV) OC43, 229E, NL63, and HKU1 (5.3%); and human metapneumovirus (HMPV; 5.0%). RSV (26 of 31 specimens [83.9%]), PIV (30 of 39 [76.9%]), and HRV (64 of 99 [64.6%]) were most common among children <5 years of age. Coinfections were found in 53 of 365 positive specimens (14.5%), and most (71.7%) were in children <5 years of age. While influenza virus, enterovirus, RSV, and HMPV had a defined period of circulation, the other viruses were detected throughout the year.CONCLUSIONS:
We found that respiratory viruses play an important role in the etiology of ILI in Cameroon, particularly in children <5 years of age.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Respiratory Tract Infections
/
RNA Viruses
/
Virus Diseases
Type of study:
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limits:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Child
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Child, preschool
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Female
/
Humans
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Infant
/
Male
Country/Region as subject:
Africa
Language:
En
Journal:
J Infect Dis
Year:
2012
Document type:
Article
Affiliation country: