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Orphan nuclear receptor TLX functions as a potent suppressor of oncogene-induced senescence in prostate cancer via its transcriptional co-regulation of the CDKN1A (p21(WAF1) (/) (CIP1) ) and SIRT1 genes.
Wu, Dinglan; Yu, Shan; Jia, Lin; Zou, Chang; Xu, Zhenyu; Xiao, Lijia; Wong, Kam-Bo; Ng, Chi-Fai; Chan, Franky L.
Affiliation
  • Wu D; School of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong, People's Republic of China.
J Pathol ; 236(1): 103-15, 2015 May.
Article in En | MEDLINE | ID: mdl-25557355

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Receptors, Cytoplasmic and Nuclear / Cyclin-Dependent Kinase Inhibitor p21 / Sirtuin 1 Limits: Animals / Humans / Male Language: En Journal: J Pathol Year: 2015 Document type: Article Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Receptors, Cytoplasmic and Nuclear / Cyclin-Dependent Kinase Inhibitor p21 / Sirtuin 1 Limits: Animals / Humans / Male Language: En Journal: J Pathol Year: 2015 Document type: Article Country of publication: