[Role of brain lipid sensing in nervous regulation of energy balance]. / Rôle de la détection centrale des lipides dans le contrôle nerveux de la balance énergétique.
Med Sci (Paris)
; 31(4): 397-403, 2015 Apr.
Article
in Fr
| MEDLINE
| ID: mdl-25958758
ABSTRACT
Fatty acid sensitive neurons located in hypothalamus, hippocampus or striatum are able to detect daily variations of plasma fatty acid levels. Thus, these neurons play a role to regulate energy balance by controling food intake, insulin secretion or hepatic glucose production. Molecular mechanisms that mediate fatty acid effects include receptor FAT (fatty acid transporter)/CD36. Deregulation of this brain lipid sensing may be an early event leading to further dysfunction of energy balance leading to obesity and type 2 diabetes.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Brain
/
Energy Metabolism
/
Lipid Metabolism
Type of study:
Diagnostic_studies
Limits:
Animals
/
Humans
Language:
Fr
Journal:
Med Sci (Paris)
Journal subject:
MEDICINA
Year:
2015
Document type:
Article
Affiliation country: