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Rapamycin restores p14, p15 and p57 expression and inhibits the mTOR/p70S6K pathway in acute lymphoblastic leukemia cells.
Li, Huibo; Kong, Xiaolin; Cui, Gang; Ren, Cuicui; Fan, Shengjin; Sun, Lili; Zhang, Yingjie; Cao, Rongyi; Li, Yinghua; Zhou, Jin.
Affiliation
  • Li H; Division of Hematology, Department of Medicine, The First Affiliated Hospital, Harbin Medical University, 23 Youzheng Street, Nan Gang District, Harbin, 150001, China.
  • Kong X; Division of Hematology, Department of Medicine, The First Affiliated Hospital, Harbin Medical University, 23 Youzheng Street, Nan Gang District, Harbin, 150001, China.
  • Cui G; Division of Hematology, Department of Medicine, The First Affiliated Hospital, Harbin Medical University, 23 Youzheng Street, Nan Gang District, Harbin, 150001, China.
  • Ren C; Division of Hematology, Department of Medicine, The First Affiliated Hospital, Harbin Medical University, 23 Youzheng Street, Nan Gang District, Harbin, 150001, China.
  • Fan S; Division of Hematology, Department of Medicine, The First Affiliated Hospital, Harbin Medical University, 23 Youzheng Street, Nan Gang District, Harbin, 150001, China.
  • Sun L; Division of Hematology, Department of Medicine, The First Affiliated Hospital, Harbin Medical University, 23 Youzheng Street, Nan Gang District, Harbin, 150001, China.
  • Zhang Y; Division of Hematology, Department of Medicine, The First Affiliated Hospital, Harbin Medical University, 23 Youzheng Street, Nan Gang District, Harbin, 150001, China.
  • Cao R; Division of Hematology, Department of Medicine, The First Affiliated Hospital, Harbin Medical University, 23 Youzheng Street, Nan Gang District, Harbin, 150001, China.
  • Li Y; Division of Hematology, Department of Medicine, The First Affiliated Hospital, Harbin Medical University, 23 Youzheng Street, Nan Gang District, Harbin, 150001, China. yinghualihmu@126.com.
  • Zhou J; Division of Hematology, Department of Medicine, The First Affiliated Hospital, Harbin Medical University, 23 Youzheng Street, Nan Gang District, Harbin, 150001, China.
Int J Hematol ; 102(5): 558-68, 2015 Nov.
Article in En | MEDLINE | ID: mdl-26362858
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Gene Expression Regulation, Leukemic / Oncogene Proteins / Sirolimus / Ribosomal Protein S6 Kinases, 70-kDa / Cyclin-Dependent Kinase Inhibitor p15 / Cyclin-Dependent Kinase Inhibitor p57 / Precursor Cell Lymphoblastic Leukemia-Lymphoma / TOR Serine-Threonine Kinases Limits: Adult / Female / Humans / Male Language: En Journal: Int J Hematol Journal subject: HEMATOLOGIA Year: 2015 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Gene Expression Regulation, Leukemic / Oncogene Proteins / Sirolimus / Ribosomal Protein S6 Kinases, 70-kDa / Cyclin-Dependent Kinase Inhibitor p15 / Cyclin-Dependent Kinase Inhibitor p57 / Precursor Cell Lymphoblastic Leukemia-Lymphoma / TOR Serine-Threonine Kinases Limits: Adult / Female / Humans / Male Language: En Journal: Int J Hematol Journal subject: HEMATOLOGIA Year: 2015 Document type: Article Affiliation country: Country of publication: