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TGF-ß2 induces epithelial-mesenchymal transition in cultured human lens epithelial cells through activation of the PI3K/Akt/mTOR signaling pathway.
Guo, Rui; Meng, Qianli; Guo, Haike; Xiao, Lijia; Yang, Xiaohong; Cui, Ying; Huang, Yu.
Affiliation
  • Guo R; Postgraduate Institute, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.
  • Meng Q; Department of Ophthalmology, Guangdong Eye Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, P.R. China.
  • Guo H; Department of Ophthalmology, Guangdong Eye Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, P.R. China.
  • Xiao L; Shenzhen Key Laboratory of Ophthalmology, Shenzhen Eye Hospital, Shenzhen, Guangdong 518034, P.R. China.
  • Yang X; Department of Ophthalmology, Guangdong Eye Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, P.R. China.
  • Cui Y; Department of Ophthalmology, Guangdong Eye Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, P.R. China.
  • Huang Y; Department of Ophthalmology, Guangdong Eye Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, P.R. China.
Mol Med Rep ; 13(2): 1105-10, 2016 Feb.
Article in En | MEDLINE | ID: mdl-26647778

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Epithelial Cells / Proto-Oncogene Proteins c-akt / Transforming Growth Factor beta2 / Phosphatidylinositol 3-Kinase / TOR Serine-Threonine Kinases / Epithelial-Mesenchymal Transition / Lens, Crystalline Limits: Humans Language: En Journal: Mol Med Rep Year: 2016 Document type: Article Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Epithelial Cells / Proto-Oncogene Proteins c-akt / Transforming Growth Factor beta2 / Phosphatidylinositol 3-Kinase / TOR Serine-Threonine Kinases / Epithelial-Mesenchymal Transition / Lens, Crystalline Limits: Humans Language: En Journal: Mol Med Rep Year: 2016 Document type: Article Country of publication: