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Bromodomain Inhibitors Correct Bioenergetic Deficiency Caused by Mitochondrial Disease Complex I Mutations.
Barrow, Joeva J; Balsa, Eduardo; Verdeguer, Francisco; Tavares, Clint D J; Soustek, Meghan S; Hollingsworth, Louis R; Jedrychowski, Mark; Vogel, Rutger; Paulo, Joao A; Smeitink, Jan; Gygi, Steve P; Doench, John; Root, David E; Puigserver, Pere.
Affiliation
  • Barrow JJ; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA 02215; Department of Cell Biology, Harvard Medical School, Boston, MA, USA 02215.
  • Balsa E; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA 02215; Department of Cell Biology, Harvard Medical School, Boston, MA, USA 02215.
  • Verdeguer F; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA 02215; Department of Cell Biology, Harvard Medical School, Boston, MA, USA 02215.
  • Tavares CD; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA 02215; Department of Cell Biology, Harvard Medical School, Boston, MA, USA 02215.
  • Soustek MS; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA 02215; Department of Cell Biology, Harvard Medical School, Boston, MA, USA 02215.
  • Hollingsworth LR; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA 02215.
  • Jedrychowski M; Department of Cell Biology, Harvard Medical School, Boston, MA, USA 02215.
  • Vogel R; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA 02215; Department of Cell Biology, Harvard Medical School, Boston, MA, USA 02215; Radboud Center for Mitochondrial Medicine, Radboud University Medical Center, Nijmegen 6500HB, the Netherlands.
  • Paulo JA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA 02215.
  • Smeitink J; Radboud Center for Mitochondrial Medicine, Radboud University Medical Center, Nijmegen 6500HB, the Netherlands.
  • Gygi SP; Department of Cell Biology, Harvard Medical School, Boston, MA, USA 02215.
  • Doench J; Broad Institute of MIT and Harvard, Cambridge, MA, USA 02142.
  • Root DE; Broad Institute of MIT and Harvard, Cambridge, MA, USA 02142.
  • Puigserver P; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA 02215; Department of Cell Biology, Harvard Medical School, Boston, MA, USA 02215; Broad Institute of MIT and Harvard, Cambridge, MA, USA 02142. Electronic address: pere_puigserver@dfci.harvard.edu.
Mol Cell ; 64(1): 163-175, 2016 10 06.
Article in En | MEDLINE | ID: mdl-27666594
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Benzodiazepines / Nuclear Proteins / Cytochrome c Group / Mitochondrial Proteins / Electron Transport Complex I / Mitochondria Type of study: Prognostic_studies Limits: Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2016 Document type: Article Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Benzodiazepines / Nuclear Proteins / Cytochrome c Group / Mitochondrial Proteins / Electron Transport Complex I / Mitochondria Type of study: Prognostic_studies Limits: Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2016 Document type: Article Country of publication: