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CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer.
Alfaqih, Mahmoud A; Nelson, Erik R; Liu, Wen; Safi, Rachid; Jasper, Jeffery S; Macias, Everardo; Geradts, Joseph; Thompson, J Will; Dubois, Laura G; Freeman, Michael R; Chang, Ching-Yi; Chi, Jen-Tsan; McDonnell, Donald P; Freedland, Stephen J.
Affiliation
  • Alfaqih MA; Department of Surgery, Duke University, Durham, North Carolina.
  • Nelson ER; Department of Pharmacology and Cancer Biology, Duke University, Durham, North Carolina.
  • Liu W; Department of Pharmacology and Cancer Biology, Duke University, Durham, North Carolina.
  • Safi R; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign; and University of Illinois Cancer Center, Chicago, Illinois.
  • Jasper JS; Department of Pharmacology and Cancer Biology, Duke University, Durham, North Carolina.
  • Macias E; Department of Pharmacology and Cancer Biology, Duke University, Durham, North Carolina.
  • Geradts J; Department of Pharmacology and Cancer Biology, Duke University, Durham, North Carolina.
  • Thompson JW; Department of Surgery, Duke University, Durham, North Carolina.
  • Dubois LG; Department of Surgery and Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California.
  • Freeman MR; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts.
  • Chang CY; Department of Pharmacology and Cancer Biology, Duke University, Durham, North Carolina.
  • Chi JT; Department of Proteomics and Metabolomics Shared Resource, Duke University, Durham, North Carolina.
  • McDonnell DP; Department of Proteomics and Metabolomics Shared Resource, Duke University, Durham, North Carolina.
  • Freedland SJ; Department of Surgery and Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California.
Cancer Res ; 77(7): 1662-1673, 2017 04 01.
Article in En | MEDLINE | ID: mdl-28130224
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Gene Expression Regulation, Enzymologic / Cholesterol / Cholestanetriol 26-Monooxygenase / Homeostasis Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Cancer Res Year: 2017 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Gene Expression Regulation, Enzymologic / Cholesterol / Cholestanetriol 26-Monooxygenase / Homeostasis Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Cancer Res Year: 2017 Document type: Article Country of publication: