Your browser doesn't support javascript.
loading
A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma.
Smith, Dirk; Helgason, Hannes; Sulem, Patrick; Bjornsdottir, Unnur Steina; Lim, Ai Ching; Sveinbjornsson, Gardar; Hasegawa, Haruki; Brown, Michael; Ketchem, Randal R; Gavala, Monica; Garrett, Logan; Jonasdottir, Adalbjorg; Jonasdottir, Aslaug; Sigurdsson, Asgeir; Magnusson, Olafur T; Eyjolfsson, Gudmundur I; Olafsson, Isleifur; Onundarson, Pall Torfi; Sigurdardottir, Olof; Gislason, David; Gislason, Thorarinn; Ludviksson, Bjorn Runar; Ludviksdottir, Dora; Boezen, H Marike; Heinzmann, Andrea; Krueger, Marcus; Porsbjerg, Celeste; Ahluwalia, Tarunveer S; Waage, Johannes; Backer, Vibeke; Deichmann, Klaus A; Koppelman, Gerard H; Bønnelykke, Klaus; Bisgaard, Hans; Masson, Gisli; Thorsteinsdottir, Unnur; Gudbjartsson, Daniel F; Johnston, James A; Jonsdottir, Ingileif; Stefansson, Kari.
Affiliation
  • Smith D; Amgen Inc., Discovery Research, South San Francisco, California, United States of America.
  • Helgason H; deCODE genetics / Amgen Inc., Reykjavík, Iceland.
  • Sulem P; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.
  • Bjornsdottir US; deCODE genetics / Amgen Inc., Reykjavík, Iceland.
  • Lim AC; Department of Medicine, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland.
  • Sveinbjornsson G; Amgen Inc., Discovery Research, South San Francisco, California, United States of America.
  • Hasegawa H; deCODE genetics / Amgen Inc., Reykjavík, Iceland.
  • Brown M; Amgen Inc., Discovery Research, South San Francisco, California, United States of America.
  • Ketchem RR; Amgen Inc., Discovery Research, South San Francisco, California, United States of America.
  • Gavala M; Amgen Inc., Discovery Research, South San Francisco, California, United States of America.
  • Garrett L; Amgen Inc., Discovery Research, South San Francisco, California, United States of America.
  • Jonasdottir A; Amgen Inc., Discovery Research, South San Francisco, California, United States of America.
  • Jonasdottir A; deCODE genetics / Amgen Inc., Reykjavík, Iceland.
  • Sigurdsson A; deCODE genetics / Amgen Inc., Reykjavík, Iceland.
  • Magnusson OT; deCODE genetics / Amgen Inc., Reykjavík, Iceland.
  • Eyjolfsson GI; deCODE genetics / Amgen Inc., Reykjavík, Iceland.
  • Olafsson I; The Laboratory in Mjodd, RAM, Reykjavik, Iceland.
  • Onundarson PT; Department of Clinical Biochemistry, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland.
  • Sigurdardottir O; Laboratory Hematology, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland.
  • Gislason D; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
  • Gislason T; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
  • Ludviksson BR; Department of Clinical Biochemistry, Akureyri Hospital, Akureyri, Iceland.
  • Ludviksdottir D; Department of Respiratory Medicine and Sleep, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland.
  • Boezen HM; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
  • Heinzmann A; Department of Respiratory Medicine and Sleep, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland.
  • Krueger M; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
  • Porsbjerg C; Department of Immunology, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland.
  • Ahluwalia TS; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
  • Waage J; Department of Respiratory Medicine and Sleep, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland.
  • Backer V; GRIAC research institute, Groningen, The Netherlands.
  • Deichmann KA; University Medical Center Groningen, University of Groningen, Department of Epidemiology, Groningen, The Netherlands.
  • Koppelman GH; Center for Pediatrics, Department of General Pediatrics, Adolescent Medicine and Neonatology, Medical Center - University of Freiburg, Faculty of Medicine, Freiburg, Germany.
  • Bønnelykke K; Center for Pediatrics, Department of General Pediatrics, Adolescent Medicine and Neonatology, Medical Center - University of Freiburg, Faculty of Medicine, Freiburg, Germany.
  • Bisgaard H; Department of Respiratory Medicine, Bispebjerg University Hospital, Copenhagen University, Copenhagen, Denmark.
  • Masson G; COPSAC (Copenhagen Prospective Studies on Asthma in Childhood), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
  • Thorsteinsdottir U; COPSAC (Copenhagen Prospective Studies on Asthma in Childhood), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
  • Gudbjartsson DF; Department of Respiratory Medicine, Bispebjerg University Hospital, Copenhagen University, Copenhagen, Denmark.
  • Johnston JA; Center for Pediatrics, Department of General Pediatrics, Adolescent Medicine and Neonatology, Medical Center - University of Freiburg, Faculty of Medicine, Freiburg, Germany.
  • Jonsdottir I; GRIAC research institute, Groningen, The Netherlands.
  • Stefansson K; University Medical Center Groningen, University of Groningen, Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, Groningen, The Netherlands.
PLoS Genet ; 13(3): e1006659, 2017 03.
Article in En | MEDLINE | ID: mdl-28273074
Subject(s)
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asthma / Eosinophils / Interleukin-33 / Mutation Type of study: Prognostic_studies Limits: Adolescent / Adult / Aged / Aged80 / Animals / Child / Child, preschool / Female / Humans / Infant Country/Region as subject: Europa Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2017 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asthma / Eosinophils / Interleukin-33 / Mutation Type of study: Prognostic_studies Limits: Adolescent / Adult / Aged / Aged80 / Animals / Child / Child, preschool / Female / Humans / Infant Country/Region as subject: Europa Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2017 Document type: Article Affiliation country: Country of publication: