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Patient-derived solitary fibrous tumour xenografts predict high sensitivity to doxorubicin/dacarbazine combination confirmed in the clinic and highlight the potential effectiveness of trabectedin or eribulin against this tumour.
Stacchiotti, S; Saponara, M; Frapolli, R; Tortoreto, M; Cominetti, D; Provenzano, S; Negri, T; Dagrada, G P; Gronchi, A; Colombo, C; Vincenzi, B; Badalamenti, G; Zuco, V; Renne, S L; Collini, P; Morosi, C; Dei Tos, A P; Bello, E; Pilotti, S; Casali, P G; D'Incalci, M; Zaffaroni, N.
Affiliation
  • Stacchiotti S; Medical Oncology Unit 2 (Adult Mesenchymal Tumours), Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy. Electronic address: silvia.stacchiotti@istitutotumori.mi.it.
  • Saponara M; Medical Oncology Unit 2 (Adult Mesenchymal Tumours), Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
  • Frapolli R; Department of Oncology, IRCCS - Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
  • Tortoreto M; Molecular Pharmacology Unit, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
  • Cominetti D; Molecular Pharmacology Unit, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
  • Provenzano S; Medical Oncology Unit 2 (Adult Mesenchymal Tumours), Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
  • Negri T; Laboratory of Experimental Molecular Pathology, Department of Diagnostic Pathology and Laboratory, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
  • Dagrada GP; Laboratory of Experimental Molecular Pathology, Department of Diagnostic Pathology and Laboratory, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
  • Gronchi A; Melanoma and Sarcoma Unit, Department of Surgery, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
  • Colombo C; Melanoma and Sarcoma Unit, Department of Surgery, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
  • Vincenzi B; Department of Oncology, University Campus Bio-Medico, via Alvaro del Portillo 21, Rome, Italy.
  • Badalamenti G; Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology, University of Palermo, Palermo, Italy.
  • Zuco V; Molecular Pharmacology Unit, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
  • Renne SL; Soft Tissue and Bone Pathology, Histopathology and Pediatric Pathology Unit, Department of Diagnostic Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • Collini P; Soft Tissue and Bone Pathology, Histopathology and Pediatric Pathology Unit, Department of Diagnostic Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • Morosi C; Department of Radiology, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
  • Dei Tos AP; Department of Anatomic Pathology, General Hospital of Treviso, Treviso, Italy.
  • Bello E; Department of Oncology, IRCCS - Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
  • Pilotti S; Laboratory of Experimental Molecular Pathology, Department of Diagnostic Pathology and Laboratory, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
  • Casali PG; Medical Oncology Unit 2 (Adult Mesenchymal Tumours), Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy; Oncology Department, University of Milan, Italy.
  • D'Incalci M; Department of Oncology, IRCCS - Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
  • Zaffaroni N; Molecular Pharmacology Unit, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
Eur J Cancer ; 76: 84-92, 2017 05.
Article in En | MEDLINE | ID: mdl-28284173
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pleural Neoplasms / Retroperitoneal Neoplasms / Soft Tissue Neoplasms / Antineoplastic Combined Chemotherapy Protocols / Cerebellar Neoplasms / Solitary Fibrous Tumors / Kidney Neoplasms / Meningeal Neoplasms Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Animals / Female / Humans / Male / Middle aged Language: En Journal: Eur J Cancer Year: 2017 Document type: Article Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pleural Neoplasms / Retroperitoneal Neoplasms / Soft Tissue Neoplasms / Antineoplastic Combined Chemotherapy Protocols / Cerebellar Neoplasms / Solitary Fibrous Tumors / Kidney Neoplasms / Meningeal Neoplasms Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Animals / Female / Humans / Male / Middle aged Language: En Journal: Eur J Cancer Year: 2017 Document type: Article Country of publication: